Challenges in Augmenting Randomized Trials with Observational Health Records

By Lucy D'Agostino McGowan in Invited Oral Presentation

July 29, 2019

Abstract

This talk addresses challenges with making health record data and clinical trial data compatible. The data collected in trials is collected regularly and in an organized way, while data from health records is messier and more haphazard. A clinical trial has a clear start and endpoint, while health record data is collected continuously. Additionally, clinical trial participants may be healthier than patients we see in health records. Covariates are defined in advance for a trial, but must be predicted or imputed from the health record. In this talk I will discuss some of the challenges we have encountered in trying to integrate trial data with observational health records to improve power and design new trials.

Date

July 29, 2019

Time

2:55 PM – 3:20 PM

Event

ASA Joint Statistical Meeting 2019